Major Research Areas

Oncology:
Tumour markers in gynecological cancers; oncogenes in gynaecological malignancies; tumour suppressor genes and virus in cervical and vulva cancer; chemosensitivity and drug resistance in gynaecological cancers; management of gynaecological malignancies; study of epigenetics factors in gynecological cancer development; study of mitochondrial DNA mutations in gynecological cancers; psychosocial intervention in patients with gynaecological cancers; quality of life of patients receiving chemotherapy and radiotherapy.

Reproduction:
Use of HRT in Hong Kong Chinese women; menopause and hormone replacement therapy; effects of hormone on cognitive function and mood of Chinese women; oestrogen and implantation; intrauterine insemination and ovarian stimulation in the management of subfertility; fertilization; interaction between embryo/sperm and reproductive tract; endometrial receptivity; spermatogenesis and genes on Y chromosome; mifepristone and misoprostol in fertility regulation.

Perinatology:
Hypothyroidism and iodine deficiency in pregnancy; maternal lipid profile, lipoproteins and glucose tolerance in pregnancy; epidemiology of gestational diabetes mellitus in Chinese patients; nutritional and iron status on pregnancy outcome; dietary manipulation in the treatment of diabetes in pregnancy; predictors of preterm delivery; feto-placental blood flow and placental development in normal and complicated pregnancies; regulation of placental apoptosis on outcome of normal and complicated pregnancies; role of IGF and IGF-BP in placental and fetal development, use of three-dimensional/four-dimensional ultrasound in prenatal diagnosis.

Prenatal diagnosis:
Ultrasonographic assessment of pregnancies at risk of thalassaemia; early intrauterine physiological changes of Bart's disease; biochemical and ultrasound screening for fetal Down's syndrome; clinical application of rapid aneuploidy screening; hematopoietic stem cell culture from umbilical cord blood.