Major Research Areas

Pharmacology of intravenous anaesthetic drugs :
Pharmacology of new intravenous anaesthetics (particularly propofol and remifentanil); pharmaokinetic modeling; patient-controlled and target-controlled infusion; ethnic variation in pharmacokinetics and pharmacodynamics; pharmacokinetic variations in various disease states; dose response characteristics.

Contact Person
Dr M. Irwin
Tel: 2855 3303
Fax: 2855 1654
Email: mgirwin@hkucc.hku.hk

Depth of anaesthesia monitoring :
Application of new anaesthetic depth monitors such as bispectral index (BIS) and brainstem auditory evoked potential (BAEP) monitoring; effect of anaesthetic agents on these monitors; use of these monitors to guide administration of anesthetics.

Contact Person
Dr M. Irwin
Tel: 2855 3303
Fax: 2855 1654
Email: mgirwin@hkucc.hku.hk

Perioperative haemostatic problems :
Effect of various anaesthetic agents on haemostasis; value of bedside haemostatic monitors such as thrombelastography and platelet function analysers; effect of haemodilution on coagulation.

Sedation in dental anaesthesia :
Safety of intravenous sedation; monitoring of depth of sedation; pharmacology of sedative drugs.

Contact Person
Dr C. Rodrigo
Tel: 2855 3303
Fax: 2855 1654
Email: rodrigo@hkusua.hku.hk